Definitive Clinical Oncology, Cellular Pathology & Genomic Biomarkers.
Sentinel lymph node biopsy provides accurate axillary nodal staging for breast cancer and melanoma while minimizing morbidity. The detection of micrometastases requires rigorous ultrastaging...
Bone marrow biopsy combined with multi-parameter flow cytometry immunophenotyping serves as the definitive diagnostic standard for acute leukemias, myelodysplastic syndromes, and plasma cell dyscrasias....
RECIST 1.1 criteria establish standardized objective response and progression endpoints for solid tumors in clinical trials and practice. Precise anatomical measurements dictate therapeutic efficacy...
Fluorescence In Situ Hybridization (FISH) is a gold-standard molecular cytogenetic assay utilized to detect chromosomal abnormalities, specifically gene amplification and polysomy, in solid tumors...
Comprehensive genomic profiling via next-generation sequencing enables the parallel detection of single nucleotide variants, insertions, deletions, copy number alterations, and structural rearrangements from limited...
This protocol details the analytical pathology standards for immunohistochemical detection of Programmed Death-Ligand 1 (PD-L1) and Human Epidermal Growth Factor Receptor 2 (HER2). Accurate...